News/Events & Publications

Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts

Perron U, Grassi E, Chatzipli A, Viviani M, Karakoc E, Trastulla L, Brochier LM, Isella C, Zanella ER, Klett H, Molineris I, Schueler J, Esteller M, Medico E, Conte N, McDermott U, Trusolino L, Bertotti A, Iorio F

Nat Commun (2024), 15(1), 9139

New LsrK Ligands as AI-2 Quorum Sensing Interfering Compounds against Biofilm Formation

Milli G, Pellegrini A, Listro R, Fasolini M, Pagano K, Ragona L, Pietrocola G, Linciano P, Collina S

Med Chem (2024), 67(20), 18139-18156

Present Scenario and Future Landscape of Payloads for ADCs: Focus on DNA-Interacting Agents

Valsasina B., Orsini P., Terenghi C., Ocana A.
Pharmaceuticals 2024, 17, 1338.

Visible Light Promoted Site-Specific Functionalization of α-Acyloxy Carboxamides: Unlocking a Forbidden Chemical Space in the Passerini Reaction

Brunelli F, Quartieri F, Miletto I, Pulici M, Papeo G, Tron GC

Chemistry (2024), 5;30(50), e202402175

Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors

Cervi G, D’Alessio R, Bindi S, Buffa L, Burocchi A, Canevari G, Modugno M, Motto I, Saturno G, Orsini P
Eur J Med Chem (2024), 270, 116375

Photocatalytic radical coupling of organoborates with α-Halogenated electron-poor olefins

Caldarelli M, Rezzi SJ, Colombo N, Pirali T, Papeo G
J Org Chem (2024), 5, 89(1), 633-643