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Present Scenario and Future Landscape of Payloads for ADCs: Focus on DNA-Interacting Agents
Valsasina B., Orsini P., Terenghi C., Ocana A.
Pharmaceuticals 2024, 17, 1338.
Visible Light Promoted Site-Specific Functionalization of α-Acyloxy Carboxamides: Unlocking a Forbidden Chemical Space in the Passerini Reaction
Brunelli F, Quartieri F, Miletto I, Pulici M, Papeo G, Tron GC
Chemistry (2024), Aug 21. Online ahead of print.
Discovery and optimization of 4-pyrazolyl-2-aminopyrimidine derivatives as potent spleen tyrosine kinase (SYK) inhibitors
Cervi G, D’Alessio R, Bindi S, Buffa L, Burocchi A, Canevari G, Modugno M, Motto I, Saturno G, Orsini P
Eur J Med Chem (2024), 270, 116375
Photocatalytic radical coupling of organoborates with α-Halogenated electron-poor olefins
Caldarelli M, Rezzi SJ, Colombo N, Pirali T, Papeo G
J Org Chem (2024), 5, 89(1), 633-643
A novel platform of diversified cytotoxins and targeted payloads to drive ADC innovation
P. Orsini, M. Salsa, S. Rizzi, U. Cucchi, D. Faiardi, A. Burocchi, A. Ciavolella, R. Lupi, F. Gasparri, B. Valsasina
AACR Annual Meeting 2024; April 5-10, 2024; San Diego
–Abstract 5805
Cancer Res (2024) 84 (6_Supplement)
The MPS1/TTK inhibitor, NMS-01940153, synergizes with tisotumab vedotin in colorectal cancer
G. Texido, F. Gasparri, A. Ciavolella, L. Gianellini, A. Burocchi, I. Fraietta, A.E. Pedersen, A. Ocaña, R. Colombo, D. Roberti, L. Mahnke, C. Perrera
AACR Annual Meeting 2024; April 5-10, 2024; San Diego
–Abstract 509
Cancer Res (2024) 84 (6_Supplement)
